| 제목 | What a wonderful, harmonious, and fantastic world we live in!!! | 글쓴이 | dosul | 날짜 | 2008.11.22 19:27 |
AZUZ: So, obviously, you kind of need your trachea. But one woman's new windpipe is being called a "milestone in medicine." That's because doctors built it using her own stem cells! They then inserted the organ during a recent transplant operation. It was a complete success, and some surgeons and scientists think that it could open the door for all sorts of medical advances. Dr. Sanjay Gupta takes us through the steps of this recent procedure.
DR. SANJAY GUPTA, CNN CHIEF MEDICAL CORRESPONDENT: Behind every medical breakthrough, there is a story, and you are looking at one: 30-year-old Claudia Castillo, playing with her kids. She is proof that stem cells can make a difference. Just a few months ago, a scene like this would have been impossible. Her lungs and trachea were badly damaged by a terrible bout with tuberculosis. Look here and here: critical narrowings, not enough air getting into her lungs. So, her doctors decided to build her a new airway using adult stem cells taken from her bone marrow, not from the embryonic stem cells that cause so much controversy. It has never been done before in a human.
PAOLO MACCHIARINI, SURGEON, HOSPITAL CLINIC OF BARCELONA: The jump between animal investigation and human investigation was a big sort of mystery to me as well, but we succeeded.
GUPTA: Pictures tell it best. Take a look at this: Doctors took a donor trachea from a 51-year-old man who had died. For six weeks, they methodically stripped away all the cells, leaving just a matrix, or scaffolding. Then slowly, they begin to build up a new trachea, using Claudia's stem cells and cells from a healthy part of her trachea. The transplant was next; rare shots inside the operating room. Adult stem cell transplants are not new. A heart valve was regrown in April of 2007. In 2004, scientists rebuilt bladder muscles using injected stem cells. And bone marrow is commonly transplanted to treat leukemia and other types of cancer. Four days after her transplant, doctors said Claudia's windpipe was "almost indistinguishable" from a healthy patient's. Today, she has no complications and no signs of rejecting the transplanted tissue.
CLAUDIA CASTILLO, TRANSPLANT PATIENT (TRANSLATED): It's a long process, but 4 months after they operated on me, it's much better. I'm fine now.
GUPTA: Doctors say they hope their success will open doors for future transplants to be performed, and to help even more patients return to their normal lives. Dr. Sanjay Gupta, CNN, New York.
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